abstract：:The purpose of this pilot study was to assess the efficacy of a new social cognition (SC) remediation intervention, the Social Cognition Individualized Activities Lab (SoCIAL), for subjects with schizophrenia. The training includes a module for emotion recognition and one for theory of mind. A comparison with a valida...

journal_title：Neuropsychiatric disease and treatment

authors： Palumbo D,Mucci A,Piegari G,D'Alise V,Mazza A,Galderisi S

更新日期：2017-07-20 00:00:00

abstract：PURPOSE:Major depressive disorder (MDD) is highly prevalent in patients with a chronic physical condition, and this comorbidity has a negative influence on quality of life, health care costs, self-care, morbidity, and mortality. Research has shown that collaborative care (CC) may be a cost-effective treatment. However,...

journal_title：Neuropsychiatric disease and treatment

authors： Goorden M,van der Feltz-Cornelis CM,van Steenbergen-Weijenburg KM,Horn EK,Beekman AT,Hakkaart-van Roijen L

更新日期：2017-07-18 00:00:00

abstract：BACKGROUND:Previous studies have demonstrated that long noncoding RNA cancer susceptibility candidate 2 (lncRNA CASC2) is frequently downregulated in several types of tumors and functions as a tumor-suppressive factor. However, the clinical significance and function of CASC2 in human glioma remain largely unknown. The ...

journal_title：Neuropsychiatric disease and treatment

authors： Wang R,Li Y,Zhu G,Tian B,Zeng W,Yang Y,Li Z

更新日期：2017-07-11 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Patients with Alzheimer's disease (AD) are frequently unaware of their cognitive symptoms and medical diagnosis. The term "anosognosia" is used to indicate a general lack of awareness of one's disease or disorder. The neural substrate underlying anosognosia in AD is unclear. Since anosognosia f...

journal_title：Neuropsychiatric disease and treatment

authors： Fujimoto H,Matsuoka T,Kato Y,Shibata K,Nakamura K,Yamada K,Narumoto J

更新日期：2017-07-05 00:00:00

abstract：:Natalizumab is a monoclonal antibody that acts as an α4 integrin antagonist to prevent leukocyte trafficking into the central nervous system. It is US Food and Drug Administration (FDA) approved for the treatment of relapsing-remitting multiple sclerosis (RRMS). Natalizumab demonstrated high efficacy in Phase III tria...

journal_title：Neuropsychiatric disease and treatment

authors： Brandstadter R,Katz Sand I

更新日期：2017-06-28 00:00:00

abstract：:Autistic spectrum disorder (ASD) is a neurodevelopmental disorder and has a high prevalence in children. Recently, mitochondrial oxidative stress has been proposed to be associated with ASD. Besides, SIRT1/PGC-1α signaling plays an important role in combating oxidative stress. In this study, we sought to determine the...

journal_title：Neuropsychiatric disease and treatment

authors： Bu X,Wu,Lu X,Yang L,Xu X,Wang J,Tang J

更新日期：2017-06-23 00:00:00

abstract：OBJECTIVE:In this study, we compared the prevalence rate of non-alcoholic fatty liver disease (NAFLD) between young males with schizophrenia and the general young males as the control group, and we also investigated the risk factors of NAFLD in young males with schizophrenia. MATERIALS AND METHODS:This is a large cros...

journal_title：Neuropsychiatric disease and treatment

authors： Yan J,Hou C,Liang Y

更新日期：2017-06-12 00:00:00

abstract：BACKGROUND:The body dysmorphic disorder is prevalent in general population and in psychiatric, dermatological, and plastic-surgery patients, but there lacks a structure-validated, comprehensive self-report measure of body image concerns, which is established through both exploratory and confirmatory factor analyses. M...

journal_title：Neuropsychiatric disease and treatment

authors： He W,Zheng Q,Ji Y,Shen C,Zhu Q,Wang W

更新日期：2017-05-29 00:00:00

abstract：BACKGROUND:Although most patients with relapsing-remitting multiple sclerosis (RRMS) will develop secondary progressive multiple sclerosis (SPMS), little is known about the burden of multiple sclerosis by disease subtype. This study describes the burden of disease in terms of demographics, disease severity, symptoms, h...

journal_title：Neuropsychiatric disease and treatment

authors： Gross HJ,Watson C

更新日期：2017-05-18 00:00:00

abstract：BACKGROUND:No study has examined the financial impact of relapses on schizophrenia from the perspective of Japanese society. This study aimed to estimate the societal costs in Japan caused by the relapses of schizophrenia. METHODS:The societal costs in Japan in 2013 due to relapses of schizophrenia were estimated by s...

journal_title：Neuropsychiatric disease and treatment

authors： Nakamura Y,Mahlich J

更新日期：2017-05-17 00:00:00

abstract：:A plethora of research has implicated hundreds of putative biomarkers for depression, but has not yet fully elucidated their roles in depressive illness or established what is abnormal in which patients and how biologic information can be used to enhance diagnosis, treatment and prognosis. This lack of progress is par...

journal_title：Neuropsychiatric disease and treatment

authors： Strawbridge R,Young AH,Cleare AJ

更新日期：2017-05-10 00:00:00

abstract：:With respect to the high burden of ischemic stroke and the absence of pharmacological treatment for promoting rehabilitation, promising candidates with specific effects on long-term functional recovery are highly desired. Candidates need reasonable experimental paradigms to evaluate the long-term functional outcome fo...

journal_title：Neuropsychiatric disease and treatment

authors： Jiao CX,Zhou H,Yang CX,Ma C,Yang YX,Mao RR,Xu L,Zhou QX

更新日期：2017-04-26 00:00:00

abstract：BACKGROUND:PULSE was a large, observational, multicenter study designed to evaluate the efficacy and safety of agomelatine in the treatment of major depression in patients with cardiovascular disease (CVD). METHODS:Patients with mild-to-moderate major depressive episodes, without psychotic symptoms, were treated as ou...

journal_title：Neuropsychiatric disease and treatment

authors： Medvedev VE

更新日期：2017-04-21 00:00:00

abstract：BACKGROUND:Dementia is generally characterized by cognitive impairment that can be accompanied by psychotic symptoms; for example, visual hallucinations are a core feature of dementia with Lewy bodies, and delusions are often seen in Alzheimer's disease. However, for behavioral variant of frontotemporal dementia (bvFTD...

journal_title：Neuropsychiatric disease and treatment

authors： Gossink FT,Vijverberg EG,Krudop W,Scheltens P,Stek ML,Pijnenburg YA,Dols A

更新日期：2017-04-13 00:00:00

abstract：BACKGROUND:The relationship between normal personality and hypnotic susceptibility is important for understanding mental processing and mental disorders, but it is less consistent in normal people or in patients with a psychiatric disorder. We have hypothesized that the correlation exists but varies in individuals with...

journal_title：Neuropsychiatric disease and treatment

authors： Zhang Y,Wang Y,Shen C,Ye Y,Shen S,Zhang B,Wang J,Chen W,Wang W

更新日期：2017-04-03 00:00:00

abstract：BACKGROUND:Physical exercise has well-characterized positive effects on depressive symptoms. The underlying biologic mechanisms are, however, far from established. A recently discovered mechanism has linked the enhanced conversion of kynurenine to kynurenic acid (KYNA) to an increased resilience toward stress-induced d...

journal_title：Neuropsychiatric disease and treatment

authors： Millischer V,Erhardt S,Ekblom Ö,Forsell Y,Lavebratt C

更新日期：2017-03-31 00:00:00

abstract：BACKGROUND:Major depressive disorder (MDD) significantly impacts performance of both work- and nonwork-related routine daily activities. We have shown that work productivity is significantly impaired in employed MDD patients, but the extent of impairments in nonwork-related routine activities and its association with a...

journal_title：Neuropsychiatric disease and treatment

authors： Jha MK,Teer RB,Minhajuddin A,Greer TL,Rush AJ,Trivedi MH

更新日期：2017-03-15 00:00:00

abstract：BACKGROUND:Occupational stress among mental health nurses may affect their psychological health, resulting in reduced performance. To provide high-quality, sustainable nursing care, it is necessary to identify and control the factors associated with psychological health among mental health nurses. The purpose of this s...

journal_title：Neuropsychiatric disease and treatment

authors： Sugawara N,Danjo K,Furukori H,Sato Y,Tomita T,Fujii A,Nakagami T,Kitaoka K,Yasui-Furukori N

更新日期：2017-03-13 00:00:00

abstract：BACKGROUND:To assess the efficacy and safety of oxcarbazepine (OXC) in the treatment of children with epilepsy. METHODS:Randomized controlled trials (RCTs) published in PubMed, Embase, Web of Science, Cochrane Library, Scopus, SinoMed (Chinese BioMedical Literature Service System, China), and Chinese National Knowledg...

journal_title：Neuropsychiatric disease and treatment

authors： Geng H,Wang C

更新日期：2017-03-02 00:00:00

abstract：:Orthorexia is recognized as an eating disorder, an obsessive-compulsive spectrum disorder, or a somatoform disorder. The aim of our research was to analyze nutritional behaviors for the assessment of the risk of orthorexia. The authors developed a questionnaire in which 981 respondents participated and used it as a re...

journal_title：Neuropsychiatric disease and treatment

authors： Olejniczak D,Bugajec D,Panczyk M,Brytek-Matera A,Religioni U,Czerw A,Grąbczewska A,Juszczyk G,Jabłkowska-Górecka K,Staniszewska A

更新日期：2017-02-21 00:00:00

abstract：BACKGROUND:Recent studies have suggested that the interactions among several factors affect the onset, progression, and prognosis of major depressive disorder. This study investigated how childhood abuse, neuroticism, and adult stressful life events interact with one another and affect depressive symptoms in the genera...

journal_title：Neuropsychiatric disease and treatment

authors： Ono K,Takaesu Y,Nakai Y,Shimura A,Ono Y,Murakoshi A,Matsumoto Y,Tanabe H,Kusumi I,Inoue T

更新日期：2017-02-15 00:00:00

abstract：BACKGROUND:Burden on caregivers of children/adolescents with attention-deficit/hyperactivity disorder (ADHD) is multidimensional, but incompletely understood. OBJECTIVE:To analyze caregiver burden across the concepts of work, social/family life, and parental worry/stress, in relation to selected contributing factors. ...

journal_title：Neuropsychiatric disease and treatment

authors： Fridman M,Banaschewski T,Sikirica V,Quintero J,Erder MH,Chen KS

更新日期：2017-02-07 00:00:00

abstract：:It is proposed that lithium's therapeutic effects occur indirectly by augmenting a cascade of protective "fail-safe" pathways pre-configured to activate in response to a dangerous low cell [Mg++] situation, eg, posttraumatic brain injury, alongside relative cell adenosine triphosphate depletion. Lithium activates cell...

journal_title：Neuropsychiatric disease and treatment

authors： van Woerkom AE

更新日期：2017-01-31 00:00:00

abstract：PURPOSE:To investigate the perception of dignity among patients hospitalized in a psychiatric setting using the Patient Dignity Inventory (PDI), which had been first validated in oncologic field among terminally ill patients. PATIENTS AND METHODS:After having modified two items, we administered the Italian version of ...

journal_title：Neuropsychiatric disease and treatment

authors： Di Lorenzo R,Cabri G,Carretti E,Galli G,Giambalvo N,Rioli G,Saraceni S,Spiga G,Del Giovane C,Ferri P

更新日期：2017-01-23 00:00:00

abstract：BACKGROUND:High-dose use of benzodiazepines (BZPs) reportedly causes adverse effects on cognitive function and quality of life in patients with schizophrenia. However, effects of BZPs on the clinical course of schizophrenia have not been clarified. This study was set out to investigate the association between BZPs and ...

journal_title：Neuropsychiatric disease and treatment

authors： Takita Y,Takaesu Y,Ono K,Futenma K,Shimura A,Murakoshi A,Komada Y,Inoue Y,Inoue T

更新日期：2016-12-15 00:00:00

abstract：BACKGROUND:Alzheimer's disease (AD) is considered to be a neurodegenerative disorder that is characterized by increased oxidative stress. Medicinal plants, with their antioxidant properties, have been used to cure several human diseases. The aim of the current study was to explore the protective and therapeutic effect ...

journal_title：Neuropsychiatric disease and treatment

authors： Zhou L,Tan S,Shan YL,Wang YG,Cai W,Huang XH,Liao XY,Li HY,Zhang L,Zhang BJ,Lu ZQ

更新日期：2016-12-09 00:00:00

abstract：:Ischemic stroke is one of the leading causes of brain disease, with high morbidity, disability, and mortality. MicroRNAs (miRNAs) have been identified as vital gene regulators in various types of human diseases. Accumulating evidence has suggested that aberrant expression of miRNAs play critical roles in the pathologi...

journal_title：Neuropsychiatric disease and treatment

authors： Yao S,Tang B,Li G,Fan R,Cao F

更新日期：2016-12-05 00:00:00

abstract：OBJECTIVE:Many previous reports have demonstrated significant neural anatomy changes in the brain of high myopic (HM) patients, whereas the spontaneous brain activity changes in the HM patients at rest are not well studied. Our objective was to use amplitude of low-frequency fluctuation (ALFF) method to investigate the...

journal_title：Neuropsychiatric disease and treatment

authors： Huang X,Zhou FQ,Hu YX,Xu XX,Zhou X,Zhong YL,Wang J,Wu XR

更新日期：2016-11-14 00:00:00

abstract：:Stroke is one of the common causes of death and disability in the world. The intraluminal middle cerebral artery occlusion/reperfusion (MCAO/R) model is a "gold standard" in surgical ischemic stroke models. Here, we optimized the procedure of this model by ligating on external carotid artery (ECA) stump and two ligatu...

journal_title：Neuropsychiatric disease and treatment

authors： Cai Q,Xu G,Liu J,Wang L,Deng G,Liu J,Chen Z

更新日期：2016-11-03 00:00:00

abstract：:Autoimmune encephalitis is a rare and newly described group of diseases involving autoantibodies directed against synaptic and neuronal cell surface antigens. It comprises a wide range of neuropsychiatric symptoms. Sensitive and specific diagnostic tests such as cell-based assay are primordial for the detection of neu...

journal_title：Neuropsychiatric disease and treatment

authors： Bost C,Pascual O,Honnorat J

更新日期：2016-10-27 00:00:00

abstract：:In the present study, we investigated the relationship between physical activity (PA) and self-esteem (SE), while introducing body mass index (BMI), perceived physical fitness (PPF), and body image (BI) in adults (N =264, M =38.10 years). The findings indicated that PA was directly and indirectly associated with SE. B...

journal_title：Neuropsychiatric disease and treatment

authors： Zamani Sani SH,Fathirezaie Z,Brand S,Pühse U,Holsboer-Trachsler E,Gerber M,Talepasand S

更新日期：2016-10-12 00:00:00

abstract：BACKGROUND:Mirtazapine, which is classified as a noradrenergic and specific serotonergic antidepressant, is widely prescribed for the treatment of major depressive disorder. The potential predictive factors of the efficacy of mirtazapine and the tolerability based on the incidence of oversedation and jitteriness/anxiet...

journal_title：Neuropsychiatric disease and treatment

authors： Tsutsumi T,Sugawara H,Ito R,Asano M,Shimizu S,Ishigooka J,Nishimura K

更新日期：2016-10-05 00:00:00

abstract：BACKGROUND:The aim of this study was to examine the impact of somatic illnesses, electrolyte imbalance, red blood cell count, hypotension, and antipsychotic and opioid treatment on the duration of delirium in Central Intensive Care Unit for Surgery. PATIENTS AND METHODS:Patients who were admitted to the Department of ...

journal_title：Neuropsychiatric disease and treatment

authors： Horacek R,Krnacova B,Prasko J,Latalova K

更新日期：2016-09-22 00:00:00

abstract：OBJECTIVES:Although bipolar disorder has been understood classically as a cyclic disease with full recovery between mood episodes, in the last decade, evidence has accumulated supporting progressive features. The clinical picture of advanced or end-stage bipolar disorder is heterogeneous with possible deficits in cogni...

journal_title：Neuropsychiatric disease and treatment

authors： Dols A,Krudop W,Möller C,Shulman K,Sajatovic M,Pijnenburg YA

更新日期：2016-09-07 00:00:00

abstract：BACKGROUND:Latest studies show that low-energy extracorporeal shock wave therapy (ESWT) can upregulate levels of vascular endothelial growth factor (VEGF). VEGF can ease nervous tissue harm after spinal cord injury (SCI). This study aims to explore whether low-energy ESWT can promote expression of VEGF, protect nervous...

journal_title：Neuropsychiatric disease and treatment

authors： Wang L,Jiang Y,Jiang Z,Han L

更新日期：2016-08-31 00:00:00

abstract：:Tuberous sclerosis complex (TSC) is a relatively rare genetic disorder, affecting one in 6,000 births. Mammalian target of rapamycin (mTOR) inhibitors, such as everolimus, which have been previously used to prevent solid organ transplant rejection, augment anticancer treatment regimens, and prevent neovascularization ...

journal_title：Neuropsychiatric disease and treatment

authors： Capal JK,Franz DN

更新日期：2016-08-25 00:00:00

abstract：BACKGROUND:This study aimed to evaluate synthetic cannabinoid (SC)-induced psychosis in terms of patient profile and clinical characteristics with reference to concurrently hospitalized schizophrenic patients. METHODS:A total of 81 male patients diagnosed with psychotic disorder induced by the use of SCs (n=50; mean (...

journal_title：Neuropsychiatric disease and treatment

authors： Altintas M,Inanc L,Oruc GA,Arpacioglu S,Gulec H

更新日期：2016-08-02 00:00:00

abstract：BACKGROUND:Preliminary placebo-controlled evidence paved the ground to the US Food and Drug Administration approval extension of lisdexamfetamine for the treatment of moderate-to-severe binge eating disorder (BED) in adults. OBJECTIVES:To provide a preliminary qualitative and quantitative synthesis of the placebo-cont...

journal_title：Neuropsychiatric disease and treatment

authors： Fornaro M,Solmi M,Perna G,De Berardis D,Veronese N,Orsolini L,Ganança L,Stubbs B

更新日期：2016-07-25 00:00:00

abstract：:Autism spectrum disorder (ASD) is a common neurodevelopmental disorder characterized by pervasive difficulties since early childhood across reciprocal social communication and restricted, repetitive interests and behaviors. Although early ASD research focused primarily on children, there is increasing recognition that...

journal_title：Neuropsychiatric disease and treatment

authors： Murphy CM,Wilson CE,Robertson DM,Ecker C,Daly EM,Hammond N,Galanopoulos A,Dud I,Murphy DG,McAlonan GM

更新日期：2016-07-07 00:00:00

abstract：BACKGROUND:Multiple sclerosis (MS) is the most common chronic autoimmune demyelinating and inflammatory disease of the central nervous system, afflicting both the body and mind. The risk of suffering from MS is 2.5-3.5 times greater in females than in males. While there is extant research on fatigue, depression, and co...

journal_title：Neuropsychiatric disease and treatment

authors： Sadeghi Bahmani D,Gerber M,Kalak N,Lemola S,Clough PJ,Calabrese P,Shaygannejad V,Pühse U,Holsboer-Trachsler E,Brand S

更新日期：2016-06-27 00:00:00